The influence of Ki-67 proliferation index on Tc-99m-EDDA-HYNIC-TOC somatostatin receptor scintigraphy in patients with carcinoids
نویسندگان
چکیده
منابع مشابه
[Parascapular lipoma with expression of somatostatin receptors detected by (99m)Tc-EDDA/HYNIC-TOC scintigraphy].
A 62-year-old woman diagnosed with a pancreatic neuroendocrine tumor (NET) underwent surgery in 2004 and was reoperated in 2009 for recurrence in the greater curvature of the stomach. Theposterior clinical and radiological controlswerenegative until 2011. InMarch 2011 a somatostatin receptor scintigraphy with 99mTcEDDA/HYNIC-TOC was performed to rule out new recurrence which was suspected due t...
متن کامل“In-house” preparation of 99mTc-EDDA/HYNIC-TOC, a specific targeting agent for somatostatin receptor scintigraphy
The use of radiolabeled peptide ligands as diagnostics and therapeutics in nuclear oncology has increased recently. One of the most frequently used radiopharmaceutical is 99mTc-EDDA/HYNIC-TOC, a somatostatin analog with affinity for certain types of somatostatin receptors, overexpressed in tumors of neuroendocrine origin. The radiopharmaceutical is not readily available; therefore we introduced...
متن کاملA visual and semi-quantitative assessment of (99m)Tc-EDDA/HYNIC-TOC scintigraphy in differentiation of solitary pulmonary nodules.
BACKGROUND The aim of the study was the assessment of the clinical usefulness of scintigraphy with (99m)Tc-EDDA/HYNIC-TOC for purposes of a differential diagnosis of SPNs by means of a visual inspection and semi-quantitative assessment of uptake intensity of the radiopharmaceutical (RPh). MATERIAL AND METHODS In 53 patients (32 males and 21 females at the ages between 38 and 78 years, mean va...
متن کاملAn intrapatient comparison of 99mTc-EDDA/HYNIC-TOC with 111In-DTPA-octreotide for diagnosis of somatostatin receptor-expressing tumors.
UNLABELLED The aim of this study was to compare the imaging abilities of the recently developed somatostatin analog, (99m)Tc-hydrazinonicotinyl-Tyr(3)-octreotide ((99m)Tc-HYNIC-TOC [(99m)Tc-TOC]), with (111)In-diethylenediaminepentaacetic acid-D-Phe(1)-octreotide ((111)In-OCT [Octreoscan]) in patients undergoing routine somatostatin receptor (SSTR) scintigraphy. METHODS Forty-one patients (20...
متن کاملThe utility of two somatostatin analog radiopharmaceuticals in assessment of radiologically indeterminate pulmonary lesions.
PURPOSE The aim of our study was to assess diagnostic accuracy of Tc-99m depreotide and Tc-99m-EDDA/HYNIC-TOC scintigraphy for evaluation of pulmonary lesions that appeared ambiguous on computed tomography (CT). MATERIAL AND METHODS Forty-nine consecutive patients (37 men and 12 women; mean age, 60 ± 11 years) with 60 pulmonary lesions on chest radiography and CT were referred for nuclear ima...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Open Chemistry
سال: 2014
ISSN: 2391-5420
DOI: 10.1515/chem-2015-0042